CDC Report: Number of U.S. Adults with Diabetes Has Skyrocketed

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The U.S. Centers for Disease Control and Prevention (CDC) released the findings from its latest Morbidity and Mortality Weekly Report (MMWR) on Thursday, which focused on the prevalence of diabetes among American adults. The MMWR stated that the number of new cases of diabetes, particularly type 2 diabetes, has risen dramatically in the last 15 years across the country, especially in some of the southern states.


The report looked at self-reported data collected from the participants of the study between the years of 1995 and 2010. The data was sorted and analyzed using a CDC system known as the Behavioral Risk Factor Surveillance System to determine whether or not the average rate of diabetes had increased over time, and if so, by how much.













Here is some of the key information to emerge from the CDC’s latest MMWR release about diabetes.


* According to the MMWR, diabetes prevalence was higher than 6 percent of the adult population in only three states at the start of the study in 1995. Puerto Rico and Washington, D.C., also had a greater than 6 percent prevalence of adult diabetes at that time.


* In 2010, at the conclusion of the study, every U.S. state, along with Puerto Rico and Washington, D.C., reported a prevalence of diabetes among its adult population that was greater than or equal to 6 percent. In addition, six states as well as Puerto Rico reported a prevalence of diabetes among their adult populations of greater than or equal to 10 percent.


* All of the participants in the study were 18 years or older. The study was conducted through telephone surveys.


* According to a report by Reuters regarding the study, Oklahoma was the state that had the largest increase in the percentage of adults living within its borders who have been diagnosed with diabetes. Kentucky was next, followed by Georgia, Alabama, Washington and West Virginia.


* Linda Geiss, the lead author of the study, told CNN on Thursday that she was surprised by the research team’s findings, saying that the “level of increase was shocking to me.” Specifically, Geiss was referring to the fact that the team found that the number of adults living with diabetes increased by at least 100 percent in 18 different states over the course of their research.


* The states that charted the highest percentage increases in the number of new diabetes cases also have had some of the highest increases in the number of adults who are considered obese, according to the CNN report.


* Geiss told CNN on Thursday that a person “should know that” they “can prevent the disease or delay it” by getting more exercise, adjusting their diet, and losing weight.


Vanessa Evans is a musician and freelance writer based in Michigan, with a lifelong interest in health and nutrition issues.


Diseases/Conditions News Headlines – Yahoo! News



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Curtains for Rice's State hopes?

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By Walter Shapiro

Before the initials CIA came to stand for Covert Intimate Affairs, the battle over the next secretary of state would have been the main event of post-election November. Normally, it doesn’t get better than a brand-name Washington struggle pitting the newly reelected president against the Republican senator he defeated in 2008 over filling the Cabinet post soon to be vacated by an ex-president’s wife. 

Barack Obama’s ill-camouflaged inclination to name Susan Rice, the ambassador to the United Nations, as Hillary Clinton’s successor would normally be about as contentious as, well, a confirmation hearing for David Petraeus in 2011. Rice, an undersecretary of state in the Clinton administration, has by most accounts performed well in a job that pivots around the micro-wording of Security Council resolutions rather than grand geopolitical visions.

But all that good will evaporated when Rice, drawing the short straw as Obama’s designated foreign-policy spinner, dutifully made the rounds of the Sunday shows on Sept. 16, five days after the Libyan attacks. Repeating the White House line, Rice argued that, based on “the best information,” a “spontaneous protest” outside the American consulate in Benghazi attracted heavily armed “extremist elements” who murdered Ambassador Chris Stevens and three other Americans. 

In John McCain’s splenetic view, Rice’s TV commentary smacks of a White House cover-up, since subsequent reporting has shown that initial accounts of a triggering protest were incorrect. As McCain put it Wednesday on Fox News, threatening to filibuster the nomination, “Susan Rice should have known better and if she didn’t know better, she is not qualified.”

At Obama’s first press conference since (gasp) June, the president displayed uncharacteristic moxie in his defense of Rice, who was a key foreign-policy supporter during his 2008 primary campaign against Hillary Clinton. Obama called the attacks on Rice “outrageous” Wednesday and said that if the Republicans “think she’s an easy target, then they’ve got a problem with me.”

All this posturing could be moot if Obama taps John Kerry for secretary of state, although the 2004 Democratic nominee now seems more likely to be headed to the Pentagon to replace Leon Panetta. (The secretary of defense has become one of the last remaining white-men-only jobs in government).

And even though one of the great political novels, “Advise and Consent” by Allen Drury, is built around a confirmation fight over a would-be secretary of state, this has always been one job that the Senate has given a president wide discretion in filling. For all the Iraq-war bluster over the appointment of Condoleezza Rice, Senate Democrats mustered only 13 votes against her in 2005, the highest number of votes against a secretary of state nomination since the early 19th century.

What makes all of this relevant now – before Obama has named a Hillary Clinton replacement – is that it underscores the illogic of most Senate confirmation fights. There may be hidden but valid strategic reasons to oppose a Rice Stuff nomination at State. But it represents a blame-the-messenger stretch even by Washington standards to ensnare Rice in the aftermath of Benghazi.

As should be obvious, the U.N. ambassador has nothing directly to do with embassy security, American covert operations in the Middle East or the flow of intelligence about terrorism. All Rice was doing in her television appearances on September 16 was reciting from talking points presumably prepared by the White House national security team based on information provided by the CIA and other agencies. According to reporting by Washington Post national security columnist David Ignatius, the CIA was still clinging to its belief that the Benghazi attacks began with a spontaneous protest when Rice made her ill-fated rounds of the Sunday shows.

This is not to deny the mysteries that are swirling around the Obama administration’s response to Benghazi. All roads lead to Libya may be the unified field theory linking all current Washington scandals. The Wall Street Journal suggested in a front-page article Thursday that a major reason why Petraeus’ resignation was accepted with such alacrity was the CIA director’s determination to shield the spy agency from blame over Benghazi. The CIA’s release of its Benghazi timeline reportedly angered National Intelligence Director James Clapper, who then used the revelation of Petraeus’ affair as a cudgel to drive him out of government.

Most likely the Republican fury over Benghazi is over-wrought, but it is also easy to grasp. The often secretive Obama administration may be tempted to try to keep everything under wraps, aside from a few sanitized disclosures, in the name of national security. But while there are presumably intelligence risks that would accompany full disclosure, the alternative is letting (probably outlandish) conspiracy theories fester.

The confusion surrounding Benghazi may be attributable to the fog of war – or the fog of a presidential election campaign. In any case, the American people deserve to know what happened and whether the root causes were bad intelligence, bad luck or just bad public explanations.

Otherwise, at the most promising bring-us-together moment of his presidency, the newly reelected Obama will find himself endlessly battling over Benghazi as he attempts to forge a second-term national security team.

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Canada’s Carney says rate hikes “less imminent”

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TORONTO (Reuters) – Interest rate hikes have become less imminent than the Bank of Canada once expected, although rates are still likely to rise, central bank Governor Mark Carney said in an interview published on Saturday.


“Over time, rates are likely to increase somewhat, but over time, so a less imminent timing relative to our expectation,” Carney said in an interview with the National Post newspaper.













Canada’s economy rebounded better than most from the global economic recession, and the Bank of Canada is the only central bank in the Group of Seven leading industrialized nations that is currently hinting at higher interest rates.


But Carney has also made clear that there will be no rate rise for a while, despite high domestic borrowing rates that he sees as a major risk to a still fragile economy.


“We’ve been very clear in terms of lines of defense in addressing financial vulnerabilities,” he said in the interview. “And the most prominent one, obviously, in Canada, is household debt.”


He said the bank was monitoring the impact of four successive government moves to tighten mortgage lending, which aimed to take the froth out of a hot housing market without causing a damaging crash in prices.


A Reuters poll published on Friday showed the majority of 20 forecasters believe the government has done enough to rein in runaway prices, preventing the type of crash that devastated the U.S. market.


The experts expect Canadian housing prices to fall 10 percent over the next several years, but they do not expect the recent property boom to end in a U.S.-style collapse.


(Reporting by Janet Guttsman; Editing by Vicki Allen)


Canada News Headlines – Yahoo! News



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With TV and film production heading overseas, should Uncle Sam get into showbiz?

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LOS ANGELES (TheWrap.com) – Is it time for Uncle Sam to go Hollywood?


With the exodus of film and TV production to foreign shores – and with the states’ incentives plans frequently out-gunned by countries outside the U.S. – there is some thought that it may be time for the federal government to step in.













The idea of the federal government helping out Hollywood while it is drowning in red ink is sure to raise hackles in some quarters. But filmmaker Michael Moore, for one, thinks it’s an idea whose time has come. And he’s not alone.


“That is one good thing the government can do in terms of being helpful and supportive, whether it’s filmmaking or other artistic endeavors,” Moore told TheWrap.


And he added, it’s also time for the states to stop fighting each other with differing tax-incentive plans. “I’ve always opposed New Mexico against North Carolina, or Michigan against L.A. I don’t like that. It’s not right. We’re Americans.”


Moore is not alone.


There are reasons to keep TV and film production from going abroad. The industry provides more than 2.4 million American jobs and adds nearly $ 180 billion to the U.S. economy annually and $ 15 billion in federal and state taxes, according to the Motion Picture Association of America.


Joe Chianese, executive VP at showbiz payroll giant Entertainment Partners Financial Solutions, believes the idea of getting the feds involved makes sense.


“You watched the debates and heard both President Obama and Gov. Romney talking about how it’s all about jobs, and they talked about how the manufacturing industry has basically been lost to overseas,” Chianese told TheWrap. “Well, we’re looking at the same sort of situation with the TV and film industry if something isn’t done.”


As he spoke to TheWrap, Chianese was about to set off for Japan, where government and film-industry officials were considering an incentive program that would align them with the more than 30 foreign countries trying to lure U.S. entertainment productions.


“You can’t blame filmmakers for taking their business elsewhere,” he said. “They’re taking their work overseas for the same reasons manufacturers are: It’s cheaper.”


Until recently, the federal government provided some help. Section 181 of the current tax code lowered the cost of capital for domestic film and TV production by providing immediate expensing on the first $ 15 million of production costs. To be eligible, 75 percent of the production had to occur in the U.S.


But it expired at the end of 2011.


California Republican Congressmen David Dreier has co-authored legislation to bring 181 back for another two years, but it is mired in Congress, along with a number of other tax-law extensions.


“Jobs are our No. 1 priority, and this bill will help more people find good jobs in California and across the U.S.,” said Dreier, who represents much of the San Gabriel Valley. “We need to create an environment that will keep entertainment productions here so that caterers, makeup artists and other small businesses that support them can create jobs too.”


Amy Lemistch, executive director of the California Film Commission, shares the world view on keeping show business here.


“We see California’s runaway production problem as a global issue,” she told TheWrap “not a state vs. state issue. People are going to the U.K. and Canada as much as they are going to other states.”


Smaller nations like Sri Lanka have begun offering breaks, and others like New Zealand have ramped up state-of-the-art production infrastructures. Even Iceland recently lured the HBO series “Game of Thrones” and the feature films “Noah” and “Prometheus.”


Particularly galling to California Film Commission officials is when productions set in the state are lured overseas. Recent examples would be the now-canceled Fox TV series “Alcratraz” and the L.A.-set movie “This Means War,” both of which shot in Vancouver.


Unlike Moore, Chianese, a tax specialist who worked with the commission when it was crafting its credits program, sees the federal incentives coming on top of state credits, rather than replacing them.


“You add, say, a 15 percent jobs credit, where companies would get 15 percent of the salary of every hire they make,” he said. “Add that on top of, say, the 25 percent credit California offers, and you’re up to 40 percent credit. That would make a real difference when it comes to keeping entertainment jobs here.”


Chianese said he’d be willing to see Section 181 go away in favor of more direct and immediate incentives. But with Obama and Congress focused on cutbacks and new taxes to pare down the national debt before the end of the year, the timing’s not good now.


It will always be an uphill fight, particularly with the House of Representatives controlled by the budget-conscious GOP.


“You’d face the same question you always do with incentives, which is: Why favor one industry over another?” Chianese said.


Not to mention major blowback from the segments of the right, which see liberal politicians as too tied to Hollywood already.


As for state credits, Hollywood breathed a sigh of relief in late September when California Gov. Jerry Brown signed a two-year extension of the state’s film and TV production-tax credit program. But no one expects it to be a game-changer when it comes to California’s fight to remain the world’s production capital.


New York, for example, is offering 30 percent tax credits, has $ 420 million available and recently added a 25 to 30 percent credit for post-production work. By comparison, California offers a 25 percent credit, has just $ 100 million available and has tougher eligibility rules.


Still, Lemisch said, the extension was critical.


“It sends a signal to the production community that California is committed in the short and long term,” she said. That’s vital, she pointed out, especially for the producers of TV dramas, which are the most desirable shows to land because they’re typically an hour long and shoot multiple episodes.


California’s output of TV dramas fell more than 11 percent last year, while While New York was hitting record production levels.


California does have some built-in advantages that aren’t going away. If you’re based in Hollywood, staying here can be cheaper than going out of state even with incentives, because you’re not paying to ship equipment and transport crews. The state’s infrastructure of studios and post-production facilities is still the most extensive.


But that doesn’t mean other states aren’t beating California to the production punch.


North Carolina – which made headlines when it enticed the feature film “Battlefield Los Angeles” to shoot there instead of in L.A. – is very busy these days. The first “Hunger Games” was filmed there, as was “Iron Man 3.’ NBC’s new drama “Revolution” and Showtime’s “Homeland” are in production there now.


Georgia, too, has seen a recent surge in feature filming. Paramount’s “Flight,” Fox’s “Parental Guidance” and Warner Bros.’ “Trouble With the Curve” all shot there.


(Steve Pond contributed to this report)


TV News Headlines – Yahoo! News



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J&J, Lilly, Merck plan clinical trial site database

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(Reuters) – Johnson & Johnson, Merck & Co Inc and Eli Lilly & Co, plan to launch a one-stop database of global clinical trial sites aimed at streamlining paperwork and speeding the process for testing new drugs.


The partners have begun securing approval from as many as 100,000 clinical investigators to enter their details into the database, Andreas Koester, head of clinical trial innovation/external alliances at J&J’s Janssen unit, said in a telephone interview.













“The feedback we have gotten so far is … they can’t wait to get rid of the administrative burden and red tape,” he said.


The initiative was limited to three companies while the kinks are ironed out, but the goal is for additional pharmaceutical companies to join in.


Ten drugmakers – J&J, Lilly, Abbott Laboratories Inc, AstraZeneca Plc, Boehringer Ingelheim, Bristol-Myers Squibb Co, GlaxoSmithKline Plc, Pfizer Inc, Roche Holding AG and Sanofi SA – announced in September the formation of the nonprofit TransCelerate BioPharma with the wider goal of simplifying and standardizing trial practices.


The clinical investigator database will contain key information such as infrastructure details and good clinical practice (GCP) training records.


“GCP doesn’t get any better if the investigator takes it repeatedly,” Koester said. “We wouldn’t have to ask each site – do you have a centrifuge, or do you have a minus 70 degrees freezer?”


J&J estimated that the investigator databank will be operational by the end of the year.


(This story corrects spelling of Lilly in headline and throughout story)


(Reporting By Deena Beasley; Editing by Bob Burgdorfer)


Health News Headlines – Yahoo! News



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Rubio: ‘My trip to Iowa has nothing to do with 2016′

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Florida Sen. Marco Rubio at the 2012 Republican National Convention (Getty)


On Thursday in Washington, D.C., Florida Sen. Marco Rubio sounded very much like he's embracing his role as a rising star in the Republican Party, but he dismissed the notion that an upcoming visit to Iowa puts him on the presidential grid for 2016.


"My trip to Iowa has nothing to do with 2016," Rubio said during a wide-ranging interview at the Atlantic's Washington Ideas Forum. "I'm one of 100 senators."


Rubio noted that when he agreed to attend the Nov. 17 fundraiser for Iowa Gov. Terry Branstad he believed Mitt Romney would be the 45th president. Romney's loss in the election, he said, underscored the GOP's need to reconnect with the middle class. "If we don't, we'll have more days like last Tuesday. What makes America vibrant is a middle class. My dad is a bartender, my mom is a maid. ... [But] our country is not creating middle-class jobs" like it used to.


On Wednesday at the same forum, Republican Sens. John McCain and Lindsey Graham made headlines when they said they would do everything they could to block U.S. Ambassador Susan Rice from being appointed secretary of state should she be nominated for the position. Both have said Rice is "unqualified" and that she misrepresented the events leading up to the attack on the American Consulate in Benghazi, Libya, on Sept. 11.


On Thursday, Rubio took a more diplomatic tack, saying he would go into a confirmation hearing with an open mind and would not "prejudge" Rice.


Rubio did say, however, that questions about the attack in Benghazi would come up. "I think we need to know the truth," he said.


On the subject of the looming "fiscal cliff," Rubio said both Republicans and Democrats need to take responsibility. "The fiscal cliff is a complete and total congressional creation," he said. "It's bipartisan dumb."


Rubio, who lives in Miami, said it's also critical that the Republican Party not alienate Hispanic voters with a hard line on immigration. "Rhetoric is important," Rubio said. "We're speaking not about statistics, but about human beings."

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Beating tax cheats key to Italy’s recovery plan

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ROME (AP) — Good plumbers may be worth their weight in gold, but when one was spotted zipping around in a bright red Ferrari, Italian tax police were fast on his trail.


Stamping out entrenched tax evasion is crucial to Premier Mario Monti‘s quest to keep Italy from succumbing to the European debt crisis, and it is critical to fellow eurozone members in more dire straits, such as Greece and Spain — which are also notorious for making cheating the taxman a way of life.













Indeed, Greece’s international rescue creditors have been pressing Greece for two years to reform its ailing tax system, citing poor collection as a key factor keeping the country mired in crisis. In Spain, where tax fraud is rampant, as much as €90 billion ($ 150 billion) is lost each year to tax fraud — the equivalent of the country’s national debt, according to Spain’s main tax inspectors union.


To succeed in Italy, authorities will have to catch the legions of self-employed and small business owners who brazenly lie about their earnings, like the plumber in the eastern town of Pescara, who socked away undeclared income in 30 bank accounts, or a successful pastry shop owner in Calabria, who on his tax return claimed he was earning next to crumbs.


And those are the less sophisticated schemers.


Tax police officials say that wealthy Italians, their companies and foreigners who make their money in Italy are increasingly trying to avoid taxes by using such strategies as falsely declaring that their base of operations or residence is abroad.


Another daunting challenge is the so-called “submerged” economy, a term embracing Italians who declare only a fraction or nothing at all of their earnings — and dentists, lawyers, doctors and other big-earning professionals are frequently among the worst offenders.


Tax evasion of all types in Italy totals about euros 240 billion ($ 300 billion), or 15 percent of the country’s gross domestic product of €1.6 trillion ($ 2 trillion), tax police estimate. Winning the war on tax cheats could therefore more than wipe out the country’s budget deficit, which is expected to increase to euros 42 billion ($ 53 billion), or 2.6 percent of GDP this year. That would start knocking away at the nation’s colossal public debt of €2 trillion ($ 2.5 trillion), or 125 percent of GDP.


But “big international frauds are up,” lamented Lt. Col. Gianluca Campana, in charge of the income tax unit revenue protection office at the Guardia di Finanza, Italy’s financial police corps which reports to the Economy Ministry.


The entrenched practice by many cafes, eateries, hair dressers and similar small business of neglecting to give customers mandatory cash register receipts commonly grabs the attention in crackdowns on tax evasion in Italy.


But, cautioned Campana, “one false (big business) invoice can equal no cash register receipts for coffees for two months.”


Over all of 2011, the total of non-declared income discovered by tax police amounted to some €50 billion ($ 65 billion), of which some 20 percent was due to international tax evasion, he said. By comparison, in the first nine months of this year, tax police discovered some €40 billion in undeclared income, with 30 percent of that blamed on international tax evasion, Campana said.


With the economic crisis shrinking bottom lines, and Italy increasingly on the hunt for big-time evasion, especially by big businesses, “there is a tendency to move capital abroad, using maneuvers apparently legal but which really are not,” Campana said. A classic technique consists of declaring one’s formal residence abroad in tax havens like Monte Carlo. Also common are companies that clearly have their business base in Italy but claim it is abroad in countries with far lower tax brackets.


Campana is armed with three degrees, including a masters in tax law from Milan’s Bocconi University, the prestigious economics institute formerly headed by Monti. He brings skills to this specialized police corps that are as finely tuned as sharp-shooting.


“We are going after the big cases (of evasion) in order to rake in more money,” Campana said.


The Ferrari-driving plumber hid some €2 million ($ 2.6 million) of his income over several years by giving his customers invoices — for jobs ranging from fixing leaks to installing new bathrooms — for the actual cost of his work, but kept a second, false registry of much lower figures for tax purposes, said Pescara tax police Col. Mauro Odorisio.


Armed with a 2008 law, authorities confiscated assets belonging to the plumber equivalent to the approximately €1 million ($ 1.3 million) they contend he owed in taxes, Odorisio said.


With Ferraris in red or yellow, and snazzy Porsches parked inside, Guardia di Finanza garages practically resemble luxury car dealerships.


The cars get sold to help recoup unpaid taxes and interest.


Overall, tax revenues in Italy were up by 4.1 percent, says the Economy Ministry, when comparing figures from the first eight months of 2012 with the same period in 2011, but much of that was due to new taxes, and not necessarily a revolution in citizens’ consciences about tax obligations.


Monti’s recipe relies heavily on taxes that are nearly impossible to avoid, such as sales tax. He also revived a property tax that his populist predecessor, Premier Silvio Berlusconi, had abolished in a promise to voters.


The ministry’s report last month noted that the property tax figured prominently in the “tendency toward growth” in tax revenues. But sales tax revenue dropped slightly despite higher sales tax rates, indicating that consumers were feeling the pinch of the stagnant economy.


The heavier fiscal burden seems to have driven some honest citizens to rebel against the engrained culture of tax evasion.


The number of phone calls from the public to the tax police’s hotline to report stores, restaurants and other businesses that didn’t give customers sales receipts has almost doubled in the first nine months of this year, compared with the same period in 2011.


It’s apparently dawning on Italians that shirking taxes in the end only costs them, in terms of ever-higher levies and cutbacks in public services.


Citizens now increasingly understand that “the lack of revenue over time caused by tax evaders forced the government to stiffen the tax burden on categories where you can’t evade taxes,” Campana said, referring to workers whose taxes are deducted from paychecks. Another area where evasion is close to impossible is real estate ownership.


Odorisio noted the crackdown included extending the statute of limitations on tax evasion from six to eight years and establishing prison as a penalty for big-time evasion.


Other weapons include a measure promoted by the Monti government that limits cash payments to no more than €1,000. Paying by credit card or personal check is a relatively new habit for Italians, who are used to carrying wads of cash in their pockets, even for big-ticket items like home renovations or vacations.


Past governments in Italy sometimes resorted to tax amnesties to try to boost revenues. But critics, contending some Italians counted on such a possibility, described that strategy as only perpetuating the tax cheat culture.


Spain hasn’t had much success with its own tax amnesty introduced by the conservative government in March. That measure, expiring soon, allows undeclared assets or those hidden in tax havens to be repatriated by paying a 10 percent tax without criminal penalty. The amnesty is estimated to recuperate far less than the expected €2.5 billion ($ 3.25 billion).


Greece saw demands for tax system reform from international rescue creditors added on to conditions for future rescue loan payments, as Greek authorities acknowledged that a high-profile campaign to crack down on major tax cheats has produced disappointing results.


The cash-strapped government over the last 10 months recovered just €19 million ($ 25 million) of the €13 billion ($ 17 billion) of arrears on the list. A prominent Greek magazine publisher recently tapped anger over rich tax evaders by publishing a list of people allegedly holding Swiss bank accounts. He was acquitted this month of breaching privacy laws.


Meanwhile, Italian tax police are chasing after cheats who have shown some of the most chutzpah about not paying their fair share of taxes, like the Padua woman who advertised on the Internet that she had a couple of “cash-only” bed and breakfast rooms to let.


Tax police discovered the lodgings are part of an apartment in public housing she was given after falsely declaring she was indigent on her annual tax forms.


____


AP reporters Derek Gatopoulos in Athens and Ciaran Giles in Madrid contributed to this report.


Europe News Headlines – Yahoo! News



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Actor Channing Tatum dubbed People’s sexiest man alive

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NEW YORK (Reuters) – Actor Channing Tatum, who set female hearts fluttering in the summer movie hit “Magic Mike”, was named the sexiest man alive by People magazine on Wednesday.


“My first thought was, ‘Y’all are messing with me,” Tatum told the magazine after hearing the news.













The 32-year-old actor, who is married to actress Jenna Dewan-Tatum, is training to play an Olympic athlete in his upcoming film, “Foxcatcher”.


The couple, who have been married since 2009, are ready to start a family, according to People.


“The first number that pops into my head is three, but I just want one to be healthy and then we’ll see where we go after that,” he told the magazine.


Tatum joins a long list of Hollywood heartthrobs who also have also received the “sexiest man” title from the magazine including Brad Pitt, Johnny Depp, Ryan Reynolds, George Clooney and Matt Damon.


(Reporting by Patricia Reaney; Editing by Maureen Bavdek)


Celebrity News Headlines – Yahoo! News



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New Hope For ‘Man on Fire Syndrome’

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Pamela Costa has never known a day without agonizing pain in her legs and feet.


At age 11, the Seattle native was diagnosed with inherited erythromelalgia, a genetic condition that causes such severe pain and redness some call it “Man on Fire Syndrome.”













“Think of the feeling that you get when you come in from the cold and your hands and feet are rewarming too fast,” said Costa, 47. “I have that feeling all of the time.”


Inherited erythromelalgia is a disease of small nerves and blood vessels that causes severe pain in response to heat, pressure, exertion or stress.


“These people feel excruciating, scalding pain while putting on shoes or putting on a sweater,” said Dr. Stephen Waxman, a neuroscientist at Yale University and the West Haven Veterans Affairs Hospital. “They will keep their feet on ice to the point of getting gangrene, just to relieve the sensation.”


When Costa was growing up, playing outside would trigger the unbearable burning sensation.


“I used to come in from recess and just hold my hands on the cool metal of my school desk,” said Costa, who has more than two dozen relatives with the same affliction. “I have had cousins suffer devastating injuries from over-cooling themselves.”


Although the disease is rare, researchers are searching for clues to its cause with hopes of uncovering treatments for chronic pain of all kinds. The story starts at the molecular level within tiny nerves that conduct pain signals.


An Overactive Channel Protein


Pain comes in different forms, depending on the type of nerve that senses it. And for chronic pain patients, the pain is not quick and specific, but instead slow and sharp.


This slow pain is transmitted from the limbs and body to the brain along small nerves in the spinal cord called C-fibers. Messages move along these nerve fibers due to the action of special proteins in their membranes called channels. One specific type of channel is the Nav1.7 sodium channel, which is present in great numbers in the C-fibers of the spinal cord.


Work by Waxman and others has shown that patients with inherited erythromelalgia have a defect in their Nav1.7 channels that allows too many sodium ions to enter the C-fibers, causing an increase in the sensitivity of the nerves.


The specific atomic structure of the Nav1.7 channel has been modeled by Waxman’s lab, and the results are detailed in the current issue of Nature Communications. Armed with this new model of the Nav1.7 channel, the lab has been able to show why some patients with inherited erythromelalgia respond well to an anti-epileptic drug called Carbamazepine.


Furthermore, in studying the channel structure in many different people, Waxman and colleagues have found variations in the channel from person to person. These variations may cause some people to be more likely to experience chronic pain than others.


A New Drug Target


Patients with a completely defective Nav1.7 suffer from the opposite condition, known as congenital indifference to pain. These people do not experience pain at all, with case reports of being able to walk on hot coals without pain.


As the role of Nav1.7 in the mechanism for pain sensation becomes clearer, biotechnology and pharmaceutical companies will likely take notice, according to Waxman.


“I anticipate a race to develop Nav1.7 specific blockers,” he said.


Current drug therapies for pain include medicines like morphine, as well as aspirin and ibuprofen. While all of these decrease the sensation of pain, they also interact with other tissues such as the brain, heart and stomach, causing side effects.


Nav1.7 does not appear to be present in large quantities outside of the C-fibers of the spinal cord. As such, new drugs targeting this protein could herald a new class of pain treatments with many fewer side effects than our current drugs for pain.


Costa said she hopes to see a day where such a medicine would be available to her, providing her with full relief for the first time in her life.


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Patraeus' mistress Broadwell in classified document probe

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Paula Broadwell, the author who allegedly had an affair with former CIA
Director David Petraeus, is suspected of storing significant amounts of
military documents, including classified material, at her home,
potentially in violation of federal law.



A source familiar with case told ABC News that Broadwell admitted to the
FBI she took the documents from secure government buildings. The
government demanded that they all be given back, and when federal agents
descended on her North Carolina home on Monday night it was a
pre-arranged meeting.



Prosecutors are now determining whether to charge Broadwell with a
crime, and this morning the FBI and military are poring over the
material. The 40-year-old author, who wrote the biography on Gen.
Petraeus "All In," is cooperating and the case, which is complicated by
the fact that as an intelligence officer in the U.S. Military Reserve
she had security clearance to review the documents.



FULL COVERAGE: David Petraeus Scandal



The FBI found classified material on a computer voluntarily handed over
by Broadwell earlier in the investigation. Prosecutors will now have to
determine how important the classified material is before making a final
decision. Authorities could decide to seek disciplinary action against
her rather than pursue charges.



Senior FBI officials are expected to brief the House and Senate
Intelligence Committees today on their handling of the Petraeus
investigation. The officials are expected to lay out how the case was
developed and argue that there were no politics involved.



The case is so critical that FBI Director Robert Mueller may attend to
defend the bureau, ABC News has learned. Members of Congress have been
angry that they were not informed about the case before the story was
reported by the media, but FBI officials maintain that their guidelines
forbid them from discussing ongoing criminal cases.



This summer, Florida socialite and "honorary ambassador" to the military Jill Kelley
received anonymous emails accusing her of flaunting a friendly
relationship with military brass in Tampa. Kelley then called the FBI,
which traced those emails back to Broadwell's computer. Investigators
are said to have then found emails in Broadwell's inbox that pointed to
an intimate affair with Petraeus, who on Friday admitted to the affair
and announced his resignation as CIA director.



See the timeline of the Petraeus/Broadwell affair HERE.



The FBI has now uncovered "potentially inappropriate" emails between
Gen. John Allen, the commander of American forces in Afghanistan, and
Kelley, according to a senior U.S. defense official who is traveling with
Defense Secretary Leon Panetta. The department is reviewing between
20,000 and 30,000 documents connected to this matter, the official said.
The email exchanges between Kelley and Allen took place from 2010 to
2012.




The U.S. official said the emails were "innocuous" and mostly about
upcoming dinner parties and seeing him on TV. Allen denies he was
involved in an affair, a Pentagon official said. An intermediary for
Allen told ABC News that Allen and his wife are friends with Kelley and
her husband and most of the emails were sent from Kelley to Allen's
wife.

A U.S. official said Allen may have triggered the investigation when he
got an anonymous email a few months ago that was traced to Broadwell.
The email had a "Kelley Patrol" return address or subject line and
painted Kelley as a seductress, which Allen found alarming and mentioned
to Kelley in a subsequent email, the official said.



The official described Kelley as a "nice, bored rich socialite who drops
the honorary from her title... and tells people she is an ambassador.
She gets herself in anything related to Centcom and all the senior
people and has been for years."

MORE: Jill Kelley and Twin Closely Tied to Top Brass






Leon Panetta: 'No One Should Leap to Any Conclusions' Regarding Gen. Allen



Panetta cautioned that "no one should leap to any conclusions" about allegations against Allen over the investigation.



Panetta said he supports Allen, who has been in command in Kabul since
July 2011. He took over that summer for Petraeus, who retired from the
Army to take over as the head of the CIA.



"He certainly has my continued confidence to lead our forces and to
continue the fight," Panetta said at a news conference in Perth,
Australia, Wednesday.



Panetta declined to explain the nature of Allen's correspondence with
Kelley, connected to the scandal that led to Petraeus' resignation last
week as director of the CIA.



Secretary of State Hillary Rodham Clinton, who appeared with Panetta,
declined to comment on the Allen case, but insured the scandal has not
harmed the war effort.



"There has been a lot of conversation, as you might expect, but no
concern whatsoever being expressed to us because the mission has been
set forth and it's being carried out," Clinton said.



Allen had been nominated as the next commander of U.S. European Command
and the commander of NATO forces in Europe, and despite President
Obama's backing, the nomination has been put on hold. The change of
command at NATO is currently slated to not take place until March at the
earliest.



Allen was supposed to appear before a Senate confirmation hearing this
Thursday alongside his designated replacement, Marine Gen. Joseph
Dunford. Panetta said that while the matter is being investigated by
the Defense Department IG, Allen will remain in his post as commander of
the International Security Assistance Force, based in Kabul.

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